Phenylephrine reddit

Phenylephrine is an alpha-agonist - that is, it works at "alpha receptors" in our body. The main effects of these receptors is to cause things to squeeze, like blood vessels, for example. That's how they work on congestion - squeezed vessels = less leaky. Phenylephrine mainly works on the alpha-1 receptors, and that's what their job is - …

But phenylephrine absolutely sucks as a decongestant (which is why it is rarely sold as a solo product), and has only gained popularity since the introduction of the Combat Methamphetamine Epidemic Act of 2005 which restricted sales of the much superior decongestants, ephedrine and pseudoephedrine (which you need to purchase from behind the ...Phenylephrine also has different side effects. It “can slightly increase people’s blood pressure or a feeling of jumpiness more than other medications,” said Dr. Robert Eitches, a Los ...Phenylephrine is a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output. Reply.Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Phenylephrine is a decongestant. Ibuprofen and phenylephrine is a combination medicine used to ...Pseudoephedrine vs phenylephrine. Studies show that phenylephrine taken orally has no better effect on nasal decongestion than nothing at all. I know in the US, we have to go to the pharmacist and ask for pseudoephedrine, but it is vastly more effective than the current regular OTC formulas. FYI - You can get 5 boxes of 24 tablets at Costco for ...This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are now allowed as responses to this comment.

Medicated decongestant spray like Afrin works pretty well if you use it correctly. Give each nostral a nice coating (1 or 2 pumps) every twelve hours and it won't lose its effectiveness until after 4 or 5 days.The Acetaminophen could harm your liver depending on what dose you end up taking. Phenylephrine even at doses slightly higher than normal can end up with a rapid heartbeat/High blood pressure/anxiety/etc. Please just go back to the store and buy a brand that just has Dextromethorphan in it. If you think that scandalous, mean-spirited or downright bizarre final wills are only things you see in crazy movies, then think again. It turns out that real people who want to make a lasting impression with their final wishes die all the ...TIL that Phenylephrine, the nasal decongestant that replaced pseudoephedrine in OTC cold medicine, was shown to be ineffective vs placebo at up to 4X the recommended dose, and was not well tolerated starting at 4X the recommended dose. : r/todayilearned by teefourPeople may sometimes confuse pseudoephedrine with phenylephrine, which is an over-the-counter (OTC) medication with similar brand names, such as Sudafed PE. In this article, we look at how alcohol ...Phenylephrine is the stuff they used to replace pseudoephedrine after people start making meth with it. It's not as good, but if it gets the job done, it gets the job done. It's probably the Phenylephrine that makes it work better than just a pure antihistamine. You can probably get the same effect with any antihistamine + decongestant.Is phenylephrine just like pseudoephedrine? Regarding its effectiveness as a treatment for nasal congestion, the answer is no. In fact, some research has found that at the current recommended doses of …

Some cold medicines, both "nondrowsy" and "drowsy," will contain pseudoephedrine, so the label is your only reliable guide. Other formulations, to get around tougher US restrictions on pseudoephedrine, use phenylephrine instead, which should be OK for Japan (but it is a worthless anticongestant compared to pseudoephedrine).Phenylephrine will exacerbate the circulatory system effects of dxm and is highly advised against since it's a bad idea to take a bunch of it on its own, much less with a drug which requires great care in selecting combinations because of its wide array of physiological and neurochemical effects. Get something with dxm only and do not take this ...15 mar. 2021 ... MIST-1 study subjects received fixed-combination TR-PH, phenylephrine 2.5% (PH) or tropicamide 1% (TR). MIST-2 study subjects received TR-PH or ...Depending if it’s a dry cough or productive. Productive I’ll recommend one thats only guaifenesin and tell them they really need to take it with at least 8oz of water to thin the mucus so they can cough it up. I don’t like combination OTC. Sometimes it’s just over kill. If it’s a dry cough then I’ll skip Mucinex cause I’m looking ...

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Phenylephrine is found in common cold medicines but it doesn't actually work when taken orally, advisers said. But before you toss your meds, here's some context. Jessica is a writer on the ...Phenylephrine is an over-the-counter nasal decongestant available in 5 mg and 10 mg tablets, as well as an oral solution. It is also available in an injectable form which is only used in an inpatient setting by medical professionals for low blood pressure. Phenylephrine can be purchased without restriction or logging of the purchaser’s ...Phenylephrine : r/depression • 12 yr. ago by coolgherm Phenylephrine Does anybody know about using phenylephrine as an antidepressant. I have had a cold for the last two weeks and have been taking dayquil to combat the mucus. It has phenylephrine in it. For the last few days of taking it, I have felt better than I have in years. Phenylephrine is a type of nasal decongestant in over-the-counter (OTC) medications, such as Sudafed PE. Phenylephrine is available as a standalone …Phenylephrine, the nasal decongestant in many cold medicines, found ineffective by FDA panel. The leading decongestant used by millions of Americans looking for relief from a stuffy nose is likely ...

The phenylephrine (PE) form is no better than a placebo when taken in pill form. It only works as a decongestant when used in a liquid form on direct contact with nasal tissues. I still can't believe they actually approved the PE forms of decongestant pills.Diphenhydramine and alcohol. Last night I had a very pleasent experience mixing both diphenhydramine and alcohol. I had drank quite a bit and was fairly tipsy, and then decided to take 100mg of diphenhydramine just to see what sort of effect it would have. The DPH kicked in pretty quickly, and made me feel way more drunk then I was, like my ...Will Phenylephrine get me high? I have a bunch of Phenylephrine and I was wondering if I took this I would feel anything I have abt 34 pills and I just wanted to know if this stuff would get me high or not? This thread is archived New comments cannot be posted and votes cannot be cast 3 13 comments Best Top New Controversial Q&AEphedrine hits all adrenergic, with a slight preference for beta (breathing, HR, and some weight loss). Pseudoephedrine or phenylephrine we'll come in and bind mostly alpha, which won't do crap except raise BP. If you're in WA then just drive to Canada and buy it from a supplement store if you're close enough.May 27, 2021 · General side effects. Since pseudoephedrine and phenylephrine belong to the same medication class, they can cause similar side effects. These may include: nervousness. dizziness. sleeplessness ... Mar 1, 2022 · DEAR MAYO CLINIC: I have used decongestants over the years when I'm ill, but my doctor recently said that I should be cautious because nonprescription decongestants can have significant side effects. Is this true? ANSWER: While many people rely on nasal decongestants to help ease nasal symptoms of a cold or flu, these medications can sometimes cause […] I have a few theories that may explain why: The drug would exist already in solution, which might make it easier to separate from inactive ingredients. This would benefit those attempting to produce methamphetamine. The drug itself may damage parts of the nose. It may simply not be very bioavailable intranasally. This page says: When you bring your personal medicines into Japan up to the amount described below, you do not have to apply for "Yunyu Kakunin-sho", instead the officers at customs check the amount of your bringing medicines, and then you can bring them into Japan. Poison, Deadly poison, Prescription drug : Up to 1 month supply. Research comparing phenylephrine to a placebo in the treatment of nasal congestion has yielded mixed results, with some studies showing minimal effectiveness compared to a placebo. This lack of significant difference in symptom relief has raised questions about the efficacy of phenylephrine in some cases.Yes, there are allergy medications that are considered safe to take during pregnancy. Experts say that most oral antihistamines, such as Benadryl and Zyrtec, are likely safe during pregnancy. Several nasal steroids, including Rhinocort and Flonase, are also safe to use. Allegra isn’t a first choice to take for allergies during pregnancy due ...Some cold medicines, both "nondrowsy" and "drowsy," will contain pseudoephedrine, so the label is your only reliable guide. Other formulations, to get around tougher US restrictions on pseudoephedrine, use phenylephrine instead, which should be OK for Japan (but it is a worthless anticongestant compared to pseudoephedrine).View community ranking In the Top 5% of largest communities on Reddit. Phenylephrine Question . Hi all, want to preface my question by saying I'm a new CA1. Yesterday I took over a case where the attending had neo running at 1.5mcg/kg. I've never seen or read information that says to go above 1.0mcg/kg but was wondering why this is?

Chlorpheniramine Maleate+Phenylephrine is safe for most of the patients when taken according to the dose and duration recommended by the doctor. However, in some patients it may cause common side effects like nausea, vomiting, headache, sleepiness and other uncommon or rare side effects. If you experience any problem while taking this medicine ...

Examples of commonly used decongestants include phenylephrine and pseudoephedrine.Often these ingredients are included in multisystem cold and flu preparations. Due to the nature of medications, it is important to always read label ingredients for medications and warnings on boxes to know what you are taking and …View community ranking In the Top 5% of largest communities on Reddit. Why SBP is increased in Phenylephrine and Norepinephrine? ... SBP depends on cardiac output So according to this concept DBP should rise but not SBP , infact SBP should decrease as phenylephrine causes reflex bradycardia and this bradycardia decreases cardiac output …2 ks99 • 10 yr. ago It is not a mystery chemical, it is used as a decongestant that has largely replaced pseudoephedrine in OTC medications (pseudo is behind the counter where I'm from). I would not take anything that didn't have only DXM in though as well. It really just depends for everyone if it will give you bad side effects or not. Since you have a low tolerance to adderall, take 5mg first and see how bad the load is. If it isn't too bad, you can take more, but know that the half life of phenylephrine is about 3 hours, so it does not go away quickly. willis81808 • 9 yr. ago. 5 oct. 2023 ... Sudafed Pe (Phenylephrine) Both pseudoephedrine and phenylephrine work as decongestants by shrinking the dilated blood vessels in the nose ...Currently about 5 weeks in on 10 mg. I got a sinus infection, was wondering if anybody knows good cold medicine that's safe to take. Specifically I have tylenol sinus and headache which has Phenylephrine HCI in it. A brief search I couldn't find anything about interactions but figured I would see if anybody here had some info.This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are now allowed as responses to this comment.Nasal sprays containing either oxymetazoline or phenylephrine are the rebound congestion-inducing nasal sprays to use with caution. If a nasal spray contains either of these active ingredients, be sure to use only as directed on the label — three days or less. Afrin is the recognizable name brand choice, but, with generic options available ...Ticoll B and Shugar G. have reported that fully related these effects to a 41-year old patient suffering from paranoid psychosis as the result of use of nasal oxymetazoline spray [12]. Snow SS. has reported the addition to phenylephrine in a 26-year old patient which actually resulted in toxic psychosis [13].

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Medicated decongestant spray like Afrin works pretty well if you use it correctly. Give each nostral a nice coating (1 or 2 pumps) every twelve hours and it won't lose its effectiveness until after 4 or 5 days.View community ranking In the Top 1% of largest communities on Reddit. Bringing cold and allergy medication to Japan . Hey guys, My girlfriend and I are traveling to Japan in a couple days and she has a bit of a cold. ...Phenylephrine is a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output. Reply.Will Phenylephrine get me high? I have a bunch of Phenylephrine and I was wondering if I took this I would feel anything I have abt 34 pills and I just wanted to know if this stuff would get me high or not? This thread is archived New comments cannot be posted and votes cannot be cast 3 13 comments Best Top New Controversial Q&APhenylephrine — the ingredient deemed ineffective — took off in popularity as a replacement for pseudoephedrine. Mike Koelzer, a pharmacist in Grand Rapids, Michigan, said he doesn't expect any...Significantly more effective as a decongestant than phenylephrine. May be used in addition to pain relievers, antihistamines, cough suppressants, expectorants, or antibiotics. Some manufacturers have reformulated cough and cold preparations to contain phenylephrine rather than pseudoephedrine. Extended-release tablets may be administered once ...5 oct. 2023 ... Sudafed Pe (Phenylephrine) Both pseudoephedrine and phenylephrine work as decongestants by shrinking the dilated blood vessels in the nose ...Currently about 5 weeks in on 10 mg. I got a sinus infection, was wondering if anybody knows good cold medicine that's safe to take. Specifically I have tylenol sinus and headache which has Phenylephrine HCI in it. A brief search I couldn't find anything about interactions but figured I would see if anybody here had some info.Phenylephrine is a vasoconstrictor - which reduces sinus congestion by shrinking capillaries and veins. Also, from Wikipedia: Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo for allergy relief.Fascinating story behind that. Guaifenesin was an unapproved drug not long ago. Was in common use before the FDA came around, so it was “grandfathered”. However the FDA provided an incentive for any company who submitted it for approval - 5 years of market exclusivity. So a private equity firm shelled out a bunch of money, a company was ... ….

11. What types of medications contain sulfites? · adrenaline (epinephrine), isoprenaline, phenylephrine. · dexamethasone and some other injectable corticosteroids ...7,872. Reaction score. 3,859. Oct 19, 2009. #3. I wouldn't be surprised if pseudoephedrine did have some ADHD benefit. Its a sympathomimetic. Other medications which work on the adrenergic system such as clonidine and Venlafaxine have some ADHD benefit. However its not like we have a strong pool of data in this area.Like super fast heart rate, shaky, sweaty,anxiety, kinda dizzy. Feels like I did a fat line of bad coke. I am not a rookie or a light weight and I take actual stimulants often. I just had no idea a decongestant could make me feel like this. Is that normal? 31 août 2023 ... Phenylephrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion.Drugs: R · r-met-HuG-CSFsee Filgrastim Injection · R-Tanna® (as a combination product containing Chlorpheniramine, Phenylephrine)see Phenylephrine · R-Tannate® (as ...Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Phenylephrine is a decongestant. Ibuprofen and phenylephrine is a combination medicine used to ...Other pharmacists have expressed concerns over phenylephrine's effectiveness as a nasal decongestant,[1] and other clinicians have indicated concern for regulatory actions that reduced the availability of pseudoephedrine.[12][13] A subsequent meta-analysis by the same researchers concluded that there is insufficient evidence for its ...Desloratadin has the lowest anticholinergic effect of all H1 antihistamines. Anticholinergic meds increase your risk for neurodegenerative disorders quite a lot. Desloratadin is according to studies even more effective than Cetirizin and it has a mild mastcell stabilising effect. Considering side and long-term effects Desloratadin is definitely ... Phenylephrine reddit, [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1]